It's time to pay attention to the endometrium, including the nucleolar channel system.
نویسندگان
چکیده
The physiologic importance of the endometrium in assisted reproductive technology is now receiving much research attention. The historical importance of ultrasound for determination of endometrial pattern, thickness and contractility is reviewed and speculation provided for a possible mechanism of the adverse effect of thin endometrium on implantation.
منابع مشابه
The Nucleolar Channel System of Human Endometrium
Human endometrium taken during the early to mid-secretory portion of the menstrual cycle is studied with the electron microscope. A description of the nucleolus is given. In addition, an unusual structure within the endometrial cell nucleolus is described, consisting of amorphous matrix, 150-A dense granules, and a series of tubular channels. This structure is named the nucleolar channel system...
متن کاملIntranuclear endoplasmic reticulum induced by Nopp140 mimics the nucleolar channel system of human endometrium.
Exogenous expression of the characteristic repeat domain of the nucleolar chaperone Nopp140 induces the formation of intranuclear structures, termed R-rings. Here, the R-rings are identified as extensive stacks of membrane cisternae in the otherwise membrane-free nucleus. They consist of bona fide endoplasmic reticulum (ER) containing integral membrane proteins of the smooth and rough ER. Altho...
متن کاملExpression of VLA1, VLA2 and VLA3 Integrin Molecules in Uterine Endometrium of Infertile Women with Unexplained Aetiology in Ahwaz-Iran
Background: Recent attention has focused on the expression of integrin molecules within the endometrium, and their relation to infertility. Objective: The present prospective study was undertaken to determine whether the endometrium of women with unexplained infertility differs in the expression of very late activation antigens (VLA) from the endometrium of normal fertile women. Methods: Thirty...
متن کاملThe nucleolar channel system of human endometrium is related to endoplasmic reticulum and R-rings.
The nucleolar channel system (NCS) is a well-established ultrastructural hallmark of the postovulation endometrium. Its transient presence has been associated with human fertility. Nevertheless, the biogenesis, composition, and function of these intranuclear membrane cisternae are unknown. Membrane systems with a striking ultrastructural resemblance to the NCS, termed R-rings, are induced in nu...
متن کاملThe nucleolar channel system reliably marks the midluteal endometrium regardless of fertility status: a fresh look at an old organelle.
OBJECTIVE To determine whether nucleolar channel systems (NCSs) in the midluteal endometrium are associated with overall fertility status and/or with unexplained infertility. DESIGN Retrospective and prospective clinical studies. SETTING Repository of stored specimens from prior multicenter study and private infertility center. PATIENT(S) Retrospective study that included 97 women (49 fer...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Fertility and sterility
دوره 96 3 شماره
صفحات -
تاریخ انتشار 2011